Physiological and pathological functions of the prion protein homologue Dpl
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چکیده
منابع مشابه
Physiological and pathological functions of the prion protein homologue Dpl.
A misfolded version of the prion protein PrP(C), known as PrP(Sc), is the major component of scrapie infectivity, the pathological agent in transmissible spongiform encephalopathies. The Prnp gene that encodes the cellular PrP(C) protein was cloned almost 20 years ago, but remained without sequence or structural relatives for over a decade. Only recently a novel protein, named Doppel (Dpl), was...
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ژورنال
عنوان ژورنال: British Medical Bulletin
سال: 2003
ISSN: 1471-8391,0007-1420
DOI: 10.1093/bmb/66.1.35